Lindafer

Each ml contains:

• Iron-sucrose complex (iron (III) hydroxide sucrose complex) eq. elemental iron 20 mg
• Water for injection USP q.s.

• iron deficiency conditions (including iron deficiency and acute posthemorrhagic anemia) in patients who need rapid iron replenishment;
• impaired absorption of iron in the gastrointestinal tract;
• refractory to the use of oral iron supplements and the inability to ensure their regular intake;
• intolerance to oral forms of iron supplements.

Intravenously (slow stream or drip), as well as into the venous section of the dialysis system. The drug is not intended for intramuscular administration. Simultaneous administration of the full (cumulative) therapeutic dose of the drug is unacceptable. Before administering the first therapeutic dose, it is necessary to prescribe a test dose. If during the observation period, phenomena of intolerance occur, administration of the drugs should be stopped immediately. Before opening the ampoule, you need to inspect it for possible sediment and damage. Drip administration. It is preferable to administer the drug by drip infusion in order to reduce the risk of a pronounced decrease in blood pressure and the risk of the solution entering the perivenous space. Immediately before infusion, the drug must be diluted with 0.9% sodium chloride solution in a ratio of 1:20 – for example, 1 ml (20 mg of iron) in 20 ml of 0.9% sodium chloride solution. The resulting solution is administered at the following speed: 100 mg of iron – no less than 15 minutes; 200 mg – within 30 minutes; 300 mg – within 1.5 hours; 400 mg – within 2.5 hours; 500 mg – over 3.5 hours.

Before the first drip administration of a therapeutic dose of the drug, a test dose must be administered: 1 ml of the drug (20 mg iron) for adults and children weighing more than 14 kg and half the daily dose (1.5 mg iron/kg) for children weighing less than 14 kg, for 15 minutes. If there are no adverse events, the remainder of the solution should be administered at the recommended rate.

Jet injection. The drug can also be administered as an undiluted solution intravenously slowly, at a rate of 1 ml of the drug (20 mg of iron) per minute – for example, 5 ml of the drug (100 mg of iron) is administered over 5 minutes. The maximum volume of the drug should not exceed 10 ml of the drug (200 mg of iron) per injection. After the injection, the patient is recommended to fix his arm in an extended position for a while. Before the first jet injection of a therapeutic dose of the drug, a test dose should be administered: 1 ml of the drug (20 mg iron) for adults and children weighing more than 14 kg and half the daily dose (1.5 mg iron/kg) for children weighing less than 14 kg, for 1–2 minutes. If there are no adverse events during the next 15 minutes of observation, the remaining part of the solution should be administered at the recommended rate. After the injection, the patient is recommended to fix his arm in an extended position.