Positively affects lipid metabolism: reduces hyperinsulinemia in obesity by inhibiting the secretion of endogenous insulin, lowers the content of triglycerides and cholesterol in the blood plasma, increases the concentration of free fatty acids and glycerol by enhancing lipolysis.
Metfialk 500 mg: each film-coated tablet contains:
Metfialk 850 mg: each film-coated tablet contains:
Metfialk 1000 mg: each tablet contains:
Adults: monotherapy and combination therapy in combination with other oral hypoglycemic agents:
The usual starting dose is 500 mg 2-3 times a day after or during meals. It is possible to further gradually increase the dose depending on the level of glucose in the blood. The maintenance dose of the drug is usually 1500 – 2000 mg per day. To reduce side effects from the gastrointestinal tract, the daily dose should be divided into 2-3 doses. The maximum dose is 3000 mg per day, divided into three doses.
Slowly increasing the dose may improve gastrointestinal tolerance. Patients taking Metfialk in doses of 2000-3000 mg per day can be switched to taking Metfialk 1000 mg.
The maximum recommended dose is 3000 mg per day, divided into three doses.